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Welcome to the March 2020 issue of The Journal of Clinical and Aesthetic Dermatology. We begin the issue with an original research article from Janeczek et al, in which the authors used a standard Wood’s lamp to visualize porphyrins associated with Corynebacterium minutissimum (C. minutissimum) in 30 patients with inverse psoriatic plaques.
Background. Inverse psoriasis is characterized by erythematous nonscaly plaques in intertriginous regions. Similarly, erythrasma, a superficial infection caused by Corynebacterium minutissimum (C. minutissimum), is also found in skin folds with red-brown lesions, making the distinction between psoriasis and erythrasma difficult.
Background. Dr. Frederic Mohs believed that surgery can spread a melanoma; to prevent this, he applied an inactive black paste vehicle containing the active ingredient 50% zinc chloride solution to melanomas to kill and fix (i.e., preserve) tissue; this is termed fixed-tissue surgery.
Hailey-Hailey disease (HHD), or chronic benign familial pemphigus, is a rare inherited acantholytic dermatosis, characterized by chronic, recurrent vesicles, erosions, and maceration in intertriginous sites.
Neutrophilic urticarial dermatosis (NUD) is rare and poorly understood. First described in 2009, NUD has been reported in association with systemic and autoinflammatory disorders.
Background. Acne and rosacea are common chronic inflammatory skin diseases associated with psychosocial impairment, anxiety, depression, and impaired overall quality of life.
Melasma is a common pigmentation disorder with few satisfactory treatment options. The hyperpigmentation has both an epidermal and dermal component.
Background. Two extracts derived from the gastropod Cryptomphalus aspersa have been shown to have dermal regeneration properties: SCA® (secretion filtrate) with fibroblast growth factor-like activity and IFC®-CAF (cellular activating factor), a snail egg extract with skin stem cell activation activity.
Background. Biotin is popular in hair loss treatment supplements, although the frequency of its deficiency in patients with hair loss has not been established.
J Clin Aesthet Dermatol. 2020;13(3):41–44 by Lin Gao, MD, PhD and Hanmei Kang, MD; Yan Li, MD; Meiheng Lu, MD; Wenting Song, MD; Yuanli Wang, MD; Kai Li, MD, PhD;
