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David Cotter, MD, PhD: Empowering Clinical Decision-Making with Upadacitinib Data

Dr. Cotter discusses how clinical trial data can help clinicians overcome therapeutic inertia when considering JAK inhibitors for patients with moderate-to-severe atopic dermatitis. Drawing from his presentation at the DERM2026 NP/PA CME Conference, he highlights the efficacy of upadacitinib in patients aged 12 years and older while addressing common concerns surrounding its safety profile and class-wide boxed warning.

Topics Covered

  • Overcoming therapeutic inertia in atopic dermatitis treatment
  • Clinical efficacy of upadacitinib in moderate-to-severe atopic dermatitis
  • Understanding JAK inhibitor boxed warnings and their origins
  • Interpreting clinical trial safety data for upadacitinib
  • Balancing treatment benefits and potential risks
  • Supporting informed, evidence-based treatment decisions

 

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