Andrew Mastro, MS, PA-C, recounted his experience on a panel called “What’s Behind the Curtain?” where experts answered top audience questions using case-based pearls based on a presentation at DEF Essential Resource Meeting 2026 (DERM2026) NP/PA CME Conference. The panel first addressed the strategy of microdosing isotretinoin to mitigate side effects and improve quality of life for patients with recalcitrant acne. Next, they outlined approach protocols for androgenetic alopecia, emphasizing the need to align treatments like systemic therapies, injections, and lab tests with specific patient goals. Finally, Mastro shared a clinical pearl about managing mismatches between biopsy results and clinical presentations, using a case of tinea incognito to illustrate the importance of pausing and re-evaluating the diagnosis when a patient is not responding to treatment.
