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The Journal of Clinical and Aesthetic Dermatology—Providing dermatologists with peer-reviewed, evidence-based information on the latest treatment options, new techniques, and practice management issues

Current Issue: October 2019

Updates in Psoriasis Management: Based on Selected Presentations from MauiDerm 2019

Updates in Psoriasis Management: Based on Selected Presentations from MauiDerm 2019

A message from the Guest Editor and MauiDerm Program Director, George Martin, MD Dear Colleagues: Each year, Maui Derm strives to bring to the podium the most up-to-date and cutting edge scientific and clinical developments in the field of dermatology. Maui Derm 2019 was no exception—our outstanding faculty delivered a mind-numbing amount of clinical information in […]

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October 2019 Editorial Message

October 2019 Editorial Message

VOL. 12, NO. 10 • OCTOBER 2019 Dear Colleagues:  Welcome to the October 2019 issue of The Journal of Clinical and Aesthetic Dermatology. We start this issue with a study by Stein Gold et al titled, “Open-label Extension Study Evaluating Long-term Safety and Efficacy of FMX101 4% Minocycline Foam for Moderate-to-severe Acne Vulgaris.” In this […]

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Open-label Extension Study Evaluating Long-term Safety and Efficacy of FMX101 4% Minocycline Foam for Moderate-to-Severe Acne Vulgaris

Open-label Extension Study Evaluating Long-term Safety and Efficacy of FMX101 4% Minocycline Foam for Moderate-to-Severe Acne Vulgaris

J Clin Aesthet Dermatol. 2019;12(10):16–23 by Linda Stein Gold, MD; Sunil Dhawan, MD; Jonathan Weiss, MD; Zoe Diana Draelos, MD; Herman Ellman, MD; and Iain Stuart, PhD Dr. Stein Gold is with the Henry Ford Health System in Detroit, Michigan. Dr. Dhawan is with the Center for Dermatology Clinical Research, Inc., in Fremont, California. Dr. Weiss […]

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Complications of Silicone Cosmetic Procedures Among Medical Tourists from the Bronx, New York:  A Retrospective Analysis

Complications of Silicone Cosmetic Procedures Among Medical Tourists from the Bronx, New York: A Retrospective Analysis

 J Clin Aesthet Dermatol. 2019;12(10):24–28 by Crystal Zheng, MD; Jeremy Quentzel, MD; and James C. M. Brust, MD Dr. Zheng is with the Division of Infectious Diseases at Tulane University in New Orleans, Louisiana. Dr. Quentzel is with the Department of Medicine, Montefiore Medical Center & Albert Einstein College of Medicine in the Bronx, New […]

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Onychomycosis: A Review of  New and Emerging Topical and  Device-based Treatments

Onychomycosis: A Review of New and Emerging Topical and Device-based Treatments

J Clin Aesthet Dermatol. 2019;12(10):29–34 by Nisrine Kawa, MD; Kachiu C. Lee, MD, MPH; R. Rox Anderson, MD; and Lilit Garibyan, MD, PhD Drs. Kawa, Anderson, and Garibyan are with the Wellman Center for Photomedicine at Massachusetts General Hospital and the Department of Dermatology at Harvard Medical School in Boston, Massachusetts. Dr. Lee is with the […]

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Vandetanib-induced Phototoxic Drug Eruption Treated with Polypodium Leucotomos Extract: A Case Report and Review of the Literature

Vandetanib-induced Phototoxic Drug Eruption Treated with Polypodium Leucotomos Extract: A Case Report and Review of the Literature

 J Clin Aesthet Dermatol. 2019;12(10):35–38 by Abraham M. Korman, MD; Kelly A. Reynolds, BA; Fadi Nabhan, MD; Bhavana Konda, MD; Manisha H. Shah, MD; and Benjamin H. Kaffenberger, MD Drs. Korman and Kaffenberger are with the Division of Dermatology in the Department of Internal Medicine at The Ohio State University Comprehensive Cancer Center in Columbus, Ohio. Ms. […]

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Past Articles

September 2019 Editorial Message

September 2019 Editorial Message

Dear Colleagues:  Welcome to the September 2019 issue of The Journal of Clinical and Aesthetic Dermatology. We begin the issue with an article by Sidgiddi et al, which reports the results of two clinical studies: one that assessed the pharmacokinetic (PK) properties of tazarotene and tazarotenic acid in DFD-03 lotion (a 1-minute, short-contact formulation for […]

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Bioavailability, Pharmacokinetics, and Transepidermal Water Loss of Short-Contact Tazarotene Lotion 0.1% Versus Tazarotene (Tazorac®) Cream 0.1%

Bioavailability, Pharmacokinetics, and Transepidermal Water Loss of Short-Contact Tazarotene Lotion 0.1% Versus Tazarotene (Tazorac®) Cream 0.1%

by Srinivas Sidgiddi, MD; Kent Allenby, MD; Franklin Okumu, PhD; and Anirudh Gautam, MPharm Drs. Sidgiddi, Allenby, and Okumu are with Promius Pharma in Princeton, New Jersey. Mr. Gautam is with Dr. Reddy’s Laboratories SA in Basel, Switzerland. FUNDING: This study was funded and sponsored by Dr. Reddy’s Laboratories (DRL #841). DISCLOSURES: Dr. Sidgiddi, MD […]

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Topical 15% Zinc Oxide Ointment Significantly Reduces the Size of Common Warts After Four Weeks: A Randomized, Triple-blinded, Placebo-controlled Trial

Topical 15% Zinc Oxide Ointment Significantly Reduces the Size of Common Warts After Four Weeks: A Randomized, Triple-blinded, Placebo-controlled Trial

by Chankiat Songsantiphap, MD, and Pravit Asawanonda, MD, DSc Drs. Songsantiphap and Asawanonda are with the Division of Dermatology in the Department of Medicine at Chulalongkorn University in Bangkok, Thailand.  ABSTRACT: Background. There are limited number of topical agents for the treatment of common warts. Few reports show efficacy of zinc oxide for such indication. Objectives. We […]

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Prolonged Periorbicular Edema After Injection of Hyaluronic Acid for Nasojugal Groove Correction

Prolonged Periorbicular Edema After Injection of Hyaluronic Acid for Nasojugal Groove Correction

by Ricardo Augusto Sandoval Vasquez, MD; Kelly Park, MD, MSL; Katherine Braunlich, DO; Shino Bay Aguilera, DO Dr. Vasquez is with the Department of Esthetic Medicine at Rosario University in Bogota, Colombia. Dr. Park is with the Section of Dermatology in the Medicine Service Line at Edward Hines Jr. VA Hospital in Hines, Illinois. Dr. […]

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Lupus Erythematosus Lichen Planus Overlap Syndrome Mimicking Squamous Cell Carcinoma

Lupus Erythematosus Lichen Planus Overlap Syndrome Mimicking Squamous Cell Carcinoma

by Brittany Smirnov, DO, FAAD; Alexandra A. Bowles, DO; John M. Strasswimmer, MD PhD; and Carlos H. Nousari, MD Dr. Smirnov is with Dermatology Associates of the Palm Beaches in Delray Beach, Florida. Dr. Bowles is with the Larkin Community Hospital Palm Springs in Hialeah, Florida. Dr. Strasswimmer is a Clinical Professor of Dermatology at Florida […]

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Melanoma and Thyroid Carcinoma: Our Current Understanding

Melanoma and Thyroid Carcinoma: Our Current Understanding

by Danielle R. Lazzara, DO; Sonya G. Zarkhin, DO; Samuel N. Rubenstein, BS; and Brad P. Glick, DO, MPH, FAOCD, FAAD Dr. Lazzara is a Dermatology Resident (PGY-4) at Larkin Community Hospital Palm Springs, Lake Erie College of Osteopathic Medicine in Hialeah, Florida. Dr. Zarkhin is a Dermatology Resident (PGY-3) at Saint Barnabas Hospital, New York […]

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Online Exclusives

Intense Pulsed-light Therapy Significantly Improves Keratosis Pilaris: A Randomized, Double-blind, Sham Irradiation-controlled Trial

Intense Pulsed-light Therapy Significantly Improves Keratosis Pilaris: A Randomized, Double-blind, Sham Irradiation-controlled Trial

 J Clin Aesthet Dermatol. 2019;12(10):E53–E57 by Praewvanid  Maitriwong, MD; Natsinee Tangkijngamvong, MD; and Pravit Asawanonda, MD, DSc Drs. Maitriwong, Tangkijngamvong, and Asawanonda are with Division of Dermatology in the Department of Medicine, Faculty of Medicine at the Chulalongkorn University in Bangkok, Thailand. FUNDING: No funding was provided for this study. DISCLOSURES: The authors have no conflicts […]

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Patient Preferences and Comparative Outcomes Regarding Cryosurgery versus Electrodesiccation in the Removal of Truncal Seborrheic Keratoses

Patient Preferences and Comparative Outcomes Regarding Cryosurgery versus Electrodesiccation in the Removal of Truncal Seborrheic Keratoses

by Elizabeth Ethington, MD; Andia Mitri, BS; David Surprenant, MD; Michael Murphy, BS; Rebecca Rovner, MD; Jeave Reserva, MD; James Swan, MD; William Adams, PhD; Rebecca Tung, MD; and Kristin Lee, MD Drs. Ethington, Surprenant, Rovner, Reserva, Swan, Lee, and Mr. Murphy are with the Divison of Dermatology at Loyola University in Maywood, Illinois. Ms. Andia […]

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Novel Tretinoin 0.05% Lotion for the Once-daily Treatment of Moderate-to-severe Acne Vulgaris in a Preadolescent and Adolescent Population

Novel Tretinoin 0.05% Lotion for the Once-daily Treatment of Moderate-to-severe Acne Vulgaris in a Preadolescent and Adolescent Population

by Sharleen St. Surin-Lord, MD; Todd E. Schlesinger, MD, FAAD; and Eric Guenin, PharmD, PhD, MPH Dr. St. Surin-Lord is with Visage Dermatology and Aesthetics Center in Largo, Maryland. Dr. Schlesinger is with the Clinical Research Center of the Carolinas in Charleston, South Carolina. Dr. Guenin is with Ortho Dermatologics in Bridgewater, New Jersey. FUNDING: Ortho […]

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The Safe and Efficacious Use of Secretome From Fibroblasts and Adipose-derived (but not Bone Marrow-derived) Mesenchymal Stem Cells for Skin Therapeutics

The Safe and Efficacious Use of Secretome From Fibroblasts and Adipose-derived (but not Bone Marrow-derived) Mesenchymal Stem Cells for Skin Therapeutics

by Greg Maguire, PhD Dr. Maguire is with NeoGenesis, Inc. in San Diego, California.  FUNDING: No funding was provided for this study. DISCLOSURES: Dr. Maguire is a part-owner of NeoGenesis, Inc. ABSTRACT: Stem cell-based products are rapidly emerging in the marketplace as topical skin care and wound care products. Confusion is prevalent among healthcare providers and […]

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Education in Cosmetic Procedural Dermatology: Resident Experiences and Perceptions

Education in Cosmetic Procedural Dermatology: Resident Experiences and Perceptions

by Colton B. Nielson, MD; Jennifer N. Harb, MD; and Kiran Motaparthi, MD Drs. Nielson, Harb, and Motaparthi are with the Department of Dermatology at the University of Florida College of Medicine in Gainesville, Florida. FUNDING: No funding was provided for this study. DISCLOSURES:  The authors have no conflicts of interest relevant to the content […]

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Tranexamic Acid for Melasma: Evaluating the Various Formulations

Tranexamic Acid for Melasma: Evaluating the Various Formulations

by Jordan V. Wang, MD, MBE, MBA; Nikita Jhawar, BS; and Nazanin Saedi, MD Drs. Wang and Saedi are with the Department of Dermatology and Cutaneous Biology at Thomas Jefferson University in Philadelphia, Pennsylvania. Ms. Jhawar is with the Drexel University College of Medicine in Philadelphia, Pennsylvania. FUNDING: No funding was provided for this study. […]

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Emerging Authors in Dermatology

Systemic Psoriasis Therapies and Comorbid Disease in Patients with Psoriasis: A Review of Potential Risks and Benefits

Systemic Psoriasis Therapies and Comorbid Disease in Patients with Psoriasis: A Review of Potential Risks and Benefits

The editors of JCAD are pleased to present this biannual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to continue their efforts in […]

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Lymphoplasmacytic Granulomatosis Cheilitis Treated with Cheiloplasty

Lymphoplasmacytic Granulomatosis Cheilitis Treated with Cheiloplasty

The editors of JCAD are pleased to present this biannual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to continue their efforts in […]

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Topical Imiquimod Induces Severe Weakness and Myalgias After Three Applications: A Case Report

Topical Imiquimod Induces Severe Weakness and Myalgias After Three Applications: A Case Report

The editors of JCAD are pleased to present this biannual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to continue their efforts in […]

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Subcutaneous Radiofrequency Microneedling for the Treatment of Thigh Skin Laxity Caused by Weight Loss: A Case Study

Subcutaneous Radiofrequency Microneedling for the Treatment of Thigh Skin Laxity Caused by Weight Loss: A Case Study

The editors of JCAD are pleased to present this biannual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to continue their efforts in […]

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Review of the Efficacy and Safety of Topical Mahonia aquifolium for the Treatment of Psoriasis and Atopic Dermatitis

Review of the Efficacy and Safety of Topical Mahonia aquifolium for the Treatment of Psoriasis and Atopic Dermatitis

Emerging Authors in Dermatology The editors of JCAD are pleased to present this bi-annual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to […]

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Complete Resolution of Mycobacterium marinum Infection with Clarithromycin and Ethambutol: A Case Report and a Review of the Literature

Complete Resolution of Mycobacterium marinum Infection with Clarithromycin and Ethambutol: A Case Report and a Review of the Literature

Emerging Authors in Dermatology The editors of JCAD are pleased to present this bi-annual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to […]

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Recent Posts

October 2019 Digital Edition

October 2019 Digital Edition

| October 1, 2019

Click the cover below to access the October 2019 digital edition of JCAD!

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Topical Hyaluronic Acid Facial Cream with New Micronized Molecule Technology Effectively Penetrates and Improves Facial Skin Quality: Results from In-vitro, Ex-vivo, and In-vivo (Open-label) Studies

Topical Hyaluronic Acid Facial Cream with New Micronized Molecule Technology Effectively Penetrates and Improves Facial Skin Quality: Results from In-vitro, Ex-vivo, and In-vivo (Open-label) Studies

| October 1, 2019

J Clin Aesthet Dermatol. 2019;12(10):39–44 by Rachel Lubart, Phd; Inbar Yariv MSc; Dror Fixler, PhD; and Anat Lipovsky, Phd Prof. Lubart and Dr. Lipovsky are with the Chemistry Department at Bar-Ilan University in Ramat-Gan, Israel. Prof. Lubart is also with the Physics Department at Bar-Ilan University in Ramat-Gan, Israel. Ms. Yariv and Prof.. Fixler are with […]

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Coprescription of Isotretinoin and Tetracyclines for Acne is Rare: An Analysis of the National Ambulatory Medical Care Survey

Coprescription of Isotretinoin and Tetracyclines for Acne is Rare: An Analysis of the National Ambulatory Medical Care Survey

| October 1, 2019

J Clin Aesthet Dermatol. 2019;12(10):45–48 by Jeave Reserva, MD; William Adams, PhD; David Perlman, BS; Brooke Vasicek, MD; Cara Joyce, PhD; Rebecca Tung, MD; and James Swan, MD Drs. Reserva, Vasicek, Tung, and Swan are with the Division of Dermatology at Loyola University Chicago in Chicago, Illinois. Mr. Perlman is with the Stritch School of Medicine […]

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Letter to the Editor: Sudden Onset of Tooth Discoloration

Letter to the Editor: Sudden Onset of Tooth Discoloration

| October 1, 2019

Dear Editor: Tooth discoloration associated with dental hygiene products is commonplace in the field of dentistry; in dermatology, tetracycline is a known cause of tooth discoloration in children.1 We present a case of a 40-year-old Caucasian woman who developed sudden-onset tooth discoloration during her rosacea treatment, which included oral doxycycline. Intrinsic and extrinsic causes of […]

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Letter to the Editor: Atrophic Lichen Planus

Letter to the Editor: Atrophic Lichen Planus

| October 1, 2019

Dear Editor: An African American man in his 50s presented with a one-year history of a pruritic rash on his anterior shins. His past medical history was significant for a recent diagnosis of diabetes. A physical examination revealed scattered, atrophic, pink/purple papules and plaques with reticular pigment on the bilateral anterior lower legs (Figure 1). […]

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September 2019 Digital Edition

September 2019 Digital Edition

| September 1, 2019

Click the cover below to access the September 2019 digital edition of JCAD!

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