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The Journal of Clinical and Aesthetic Dermatology—Providing dermatologists with peer-reviewed, evidence-based information on the latest treatment options, new techniques, and practice management issues

Current Issue: September 2019

September 2019 Editorial Message

September 2019 Editorial Message

Dear Colleagues:  Welcome to the September 2019 issue of The Journal of Clinical and Aesthetic Dermatology. We begin the issue with an article by Sidgiddi et al, which reports the results of two clinical studies: one that assessed the pharmacokinetic (PK) properties of tazarotene and tazarotenic acid in DFD-03 lotion (a 1-minute, short-contact formulation for […]

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Bioavailability, Pharmacokinetics, and Transepidermal Water Loss of Short-Contact Tazarotene Lotion 0.1% Versus Tazarotene (Tazorac®) Cream 0.1%

Bioavailability, Pharmacokinetics, and Transepidermal Water Loss of Short-Contact Tazarotene Lotion 0.1% Versus Tazarotene (Tazorac®) Cream 0.1%

by Srinivas Sidgiddi, MD; Kent Allenby, MD; Franklin Okumu, PhD; and Anirudh Gautam, MPharm Drs. Sidgiddi, Allenby, and Okumu are with Promius Pharma in Princeton, New Jersey. Mr. Gautam is with Dr. Reddy’s Laboratories SA in Basel, Switzerland. FUNDING: This study was funded and sponsored by Dr. Reddy’s Laboratories (DRL #841). DISCLOSURES: Dr. Sidgiddi, MD […]

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Topical 15% Zinc Oxide Ointment Significantly Reduces the Size of Common Warts After Four Weeks: A Randomized, Triple-blinded, Placebo-controlled Trial

Topical 15% Zinc Oxide Ointment Significantly Reduces the Size of Common Warts After Four Weeks: A Randomized, Triple-blinded, Placebo-controlled Trial

by Chankiat Songsantiphap, MD, and Pravit Asawanonda, MD, DSc Drs. Songsantiphap and Asawanonda are with the Division of Dermatology in the Department of Medicine at Chulalongkorn University in Bangkok, Thailand.  ABSTRACT: Background. There are limited number of topical agents for the treatment of common warts. Few reports show efficacy of zinc oxide for such indication. Objectives. We […]

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Prolonged Periorbicular Edema After Injection of Hyaluronic Acid for Nasojugal Groove Correction

Prolonged Periorbicular Edema After Injection of Hyaluronic Acid for Nasojugal Groove Correction

by Ricardo Augusto Sandoval Vasquez, MD; Kelly Park, MD, MSL; Katherine Braunlich, DO; Shino Bay Aguilera, DO Dr. Vasquez is with the Department of Esthetic Medicine at Rosario University in Bogota, Colombia. Dr. Park is with the Section of Dermatology in the Medicine Service Line at Edward Hines Jr. VA Hospital in Hines, Illinois. Dr. […]

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Lupus Erythematosus Lichen Planus Overlap Syndrome Mimicking Squamous Cell Carcinoma

Lupus Erythematosus Lichen Planus Overlap Syndrome Mimicking Squamous Cell Carcinoma

by Brittany Smirnov, DO, FAAD; Alexandra A. Bowles, DO; John M. Strasswimmer, MD PhD; and Carlos H. Nousari, MD Dr. Smirnov is with Dermatology Associates of the Palm Beaches in Delray Beach, Florida. Dr. Bowles is with the Larkin Community Hospital Palm Springs in Hialeah, Florida. Dr. Strasswimmer is a Clinical Professor of Dermatology at Florida […]

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Melanoma and Thyroid Carcinoma: Our Current Understanding

Melanoma and Thyroid Carcinoma: Our Current Understanding

by Danielle R. Lazzara, DO; Sonya G. Zarkhin, DO; Samuel N. Rubenstein, BS; and Brad P. Glick, DO, MPH, FAOCD, FAAD Dr. Lazzara is a Dermatology Resident (PGY-4) at Larkin Community Hospital Palm Springs, Lake Erie College of Osteopathic Medicine in Hialeah, Florida. Dr. Zarkhin is a Dermatology Resident (PGY-3) at Saint Barnabas Hospital, New York […]

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Past Articles

August 2019 Editorial Message

August 2019 Editorial Message

Dear Colleagues:  Welcome to the August 2019 issue of The Journal of Clinical and Aesthetic Dermatology (JCAD). We begin the issue with an article by Bhargava et al, the authors detail the results of their study evaluating subcision and microneedling as a treatment for atrophic acne scars in 45 patients with dark skin at a […]

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Subcision and Microneedling as an Inexpensive and Safe Combination to Treat Atrophic Acne Scars in Dark Skin: A Prospective Study of 45 Patients at a Tertiary Care Center

Subcision and Microneedling as an Inexpensive and Safe Combination to Treat Atrophic Acne Scars in Dark Skin: A Prospective Study of 45 Patients at a Tertiary Care Center

by Shashank Bhargava, MD; Ujjwal Kumar, MD; and Krishnendra Varma, MD Bhargava, Kumar, and Varma are with the Department of Dermatology at R.D. Gardi Medical College in Ujjain, India. FUNDING: No funding was provided for this study. DISCLOSURES: The authors have no conflicts of interest relevant to the content of this article. ABSTRACT: Background. Acne scars are […]

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The Correlations between Follicular Fluorescence and Casual Sebum Levels in Subjects with Normal Skin

The Correlations between Follicular Fluorescence and Casual Sebum Levels in Subjects with Normal Skin

by Chankiat Songsantiphap, MD and Pravit Asawanonda, MD, DSc Drs. Songsantiphap and Asawanonda are with the Division of Dermatology, Department of Medicine, Faculty of Medicine at Chulalongkorn University in Bangkok, Thailand. FUNDING: No funding was provided for this study. DISCLOSURES: The authors have no conflicts of interest relevant to the content of this article. ABSTRACT: Background. Performing […]

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Impact of Smoking and Alcohol Use on Facial Aging in Women: Results of a Large Multinational, Multiracial, Cross-sectional Survey

Impact of Smoking and Alcohol Use on Facial Aging in Women: Results of a Large Multinational, Multiracial, Cross-sectional Survey

by Greg D. Goodman, MD; Joely Kaufman, MD; Doris Day, MD; Robert Weiss, MD; Ariane K. Kawata, PhD; Julia K. Garcia, PhD; Samantha Santangelo, PhD; and Conor J. Gallagher, PhD Dr. Goodman is with Monash University in Clayton, Australia and Skin & Cancer Foundation Inc., in Carlton, Australia. Dr. Kaufman is with Skin Associates of South Florida […]

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Definition, Association with Malignancy, Biologic Behavior, and Treatment of Ectopic Extramammary Paget’s Disease:  A Review of the Literature

Definition, Association with Malignancy, Biologic Behavior, and Treatment of Ectopic Extramammary Paget’s Disease: A Review of the Literature

by Chase A. Scarbrough, DO; Abby Vrable, DO; and David R. Carr, MD Drs. Scarbrough and Carr are with the Division of Dermatology at the Ohio State University in Columbus, Ohio. Dr. Vrable is with the Department of Dermatology at Boston Medical Center in Boston, Massachusetts.  FUNDING: No funding was provided for this study. DISCLOSURES: […]

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Polypodium Leucotomos Extract (PLE): New Study Gives Evidence-based Insight into “Ain’t Nothing Like the Real Thing”

Polypodium Leucotomos Extract (PLE): New Study Gives Evidence-based Insight into “Ain’t Nothing Like the Real Thing”

by James Q. Del Rosso, DO Dr. Del Rosso is with JDR Dermatology Research and Thomas Dermatology in Las Vegas, Nevada and is Adjunct Clinical Professor of Dermatology at Touro University Nevada in Henderson, Nevada. FUNDING: No funding was provided in support of this article.  DISCLOSURES: Dr. Del Rosso serves as a consultant to Ferndale […]

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Online Exclusives

Patient Preferences and Comparative Outcomes Regarding Cryosurgery versus Electrodesiccation in the Removal of Truncal Seborrheic Keratoses

Patient Preferences and Comparative Outcomes Regarding Cryosurgery versus Electrodesiccation in the Removal of Truncal Seborrheic Keratoses

by Elizabeth Ethington, MD; Andia Mitri, BS; David Surprenant, MD; Michael Murphy, BS; Rebecca Rovner, MD; Jeave Reserva, MD; James Swan, MD; William Adams, PhD; Rebecca Tung, MD; and Kristin Lee, MD Drs. Ethington, Surprenant, Rovner, Reserva, Swan, Lee, and Mr. Murphy are with the Divison of Dermatology at Loyola University in Maywood, Illinois. Ms. Andia […]

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Novel Tretinoin 0.05% Lotion for the Once-daily Treatment of Moderate-to-severe Acne Vulgaris in a Preadolescent and Adolescent Population

Novel Tretinoin 0.05% Lotion for the Once-daily Treatment of Moderate-to-severe Acne Vulgaris in a Preadolescent and Adolescent Population

by Sharleen St. Surin-Lord, MD; Todd E. Schlesinger, MD, FAAD; and Eric Guenin, PharmD, PhD, MPH Dr. St. Surin-Lord is with Visage Dermatology and Aesthetics Center in Largo, Maryland. Dr. Schlesinger is with the Clinical Research Center of the Carolinas in Charleston, South Carolina. Dr. Guenin is with Ortho Dermatologics in Bridgewater, New Jersey. FUNDING: Ortho […]

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The Safe and Efficacious Use of Secretome From Fibroblasts and Adipose-derived (but not Bone Marrow-derived) Mesenchymal Stem Cells for Skin Therapeutics

The Safe and Efficacious Use of Secretome From Fibroblasts and Adipose-derived (but not Bone Marrow-derived) Mesenchymal Stem Cells for Skin Therapeutics

by Greg Maguire, PhD Dr. Maguire is with NeoGenesis, Inc. in San Diego, California.  FUNDING: No funding was provided for this study. DISCLOSURES: Dr. Maguire is a part-owner of NeoGenesis, Inc. ABSTRACT: Stem cell-based products are rapidly emerging in the marketplace as topical skin care and wound care products. Confusion is prevalent among healthcare providers and […]

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Education in Cosmetic Procedural Dermatology: Resident Experiences and Perceptions

Education in Cosmetic Procedural Dermatology: Resident Experiences and Perceptions

by Colton B. Nielson, MD; Jennifer N. Harb, MD; and Kiran Motaparthi, MD Drs. Nielson, Harb, and Motaparthi are with the Department of Dermatology at the University of Florida College of Medicine in Gainesville, Florida. FUNDING: No funding was provided for this study. DISCLOSURES:  The authors have no conflicts of interest relevant to the content […]

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Tranexamic Acid for Melasma: Evaluating the Various Formulations

Tranexamic Acid for Melasma: Evaluating the Various Formulations

by Jordan V. Wang, MD, MBE, MBA; Nikita Jhawar, BS; and Nazanin Saedi, MD Drs. Wang and Saedi are with the Department of Dermatology and Cutaneous Biology at Thomas Jefferson University in Philadelphia, Pennsylvania. Ms. Jhawar is with the Drexel University College of Medicine in Philadelphia, Pennsylvania. FUNDING: No funding was provided for this study. […]

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Efficacy of an Antiaging Treatment Against Environmental Factors: Deschampsia antarctica Extract and High-tolerance Retinoids Combination

Efficacy of an Antiaging Treatment Against Environmental Factors: Deschampsia antarctica Extract and High-tolerance Retinoids Combination

by Azahara Pérez Davó, PhD, MSc; Maria Teresa Truchuelo, MD, PhD; Maria Vitale, MD; and J. Gonzalez-Castro, MD Dr. Perez-Davó is with the Medical Affairs Department at Cantabria Labs in Madrid, Spain. Dr. Truchuelo is with the Vithas Nuestra Señora de América Hospital in Madrid, Spain. Dr. Vitale is with the Medical Department of Cantabria […]

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Emerging Authors in Dermatology

Systemic Psoriasis Therapies and Comorbid Disease in Patients with Psoriasis: A Review of Potential Risks and Benefits

Systemic Psoriasis Therapies and Comorbid Disease in Patients with Psoriasis: A Review of Potential Risks and Benefits

The editors of JCAD are pleased to present this biannual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to continue their efforts in […]

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Lymphoplasmacytic Granulomatosis Cheilitis Treated with Cheiloplasty

Lymphoplasmacytic Granulomatosis Cheilitis Treated with Cheiloplasty

The editors of JCAD are pleased to present this biannual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to continue their efforts in […]

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Topical Imiquimod Induces Severe Weakness and Myalgias After Three Applications: A Case Report

Topical Imiquimod Induces Severe Weakness and Myalgias After Three Applications: A Case Report

The editors of JCAD are pleased to present this biannual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to continue their efforts in […]

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Subcutaneous Radiofrequency Microneedling for the Treatment of Thigh Skin Laxity Caused by Weight Loss: A Case Study

Subcutaneous Radiofrequency Microneedling for the Treatment of Thigh Skin Laxity Caused by Weight Loss: A Case Study

The editors of JCAD are pleased to present this biannual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to continue their efforts in […]

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Review of the Efficacy and Safety of Topical Mahonia aquifolium for the Treatment of Psoriasis and Atopic Dermatitis

Review of the Efficacy and Safety of Topical Mahonia aquifolium for the Treatment of Psoriasis and Atopic Dermatitis

Emerging Authors in Dermatology The editors of JCAD are pleased to present this bi-annual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to […]

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Complete Resolution of Mycobacterium marinum Infection with Clarithromycin and Ethambutol: A Case Report and a Review of the Literature

Complete Resolution of Mycobacterium marinum Infection with Clarithromycin and Ethambutol: A Case Report and a Review of the Literature

Emerging Authors in Dermatology The editors of JCAD are pleased to present this bi-annual column as a means to recognize select medical students, PhD candidates, and other young investigators in the field of dermatology for their efforts in scientific writing. We hope that the publication of their work encourages these and other emerging authors to […]

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Recent Posts

Circadian Rhythm and the Skin: A Review of the Literature

Circadian Rhythm and the Skin: A Review of the Literature

| September 1, 2019

by Alexis B. Lyons, MD; Lauren Moy, MD; Ronald Moy, MD; and Rebecca Tung, MD Dr. Lyons is with the Department of Dermatology at Henry Ford Hospital in Detroit, Michigan. Drs. L. Moy and Tung are with the Department of Dermatology at Loyola University Medical Center in Chicago, Illinois. Dr. R. Moy is with Moy, […]

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An Unusual Presentation and Aggressive Course of Metastatic Myoepithelial Carcinoma

An Unusual Presentation and Aggressive Course of Metastatic Myoepithelial Carcinoma

| September 1, 2019

by Nathalie C. Zeitouni, MDCM, FRCPC; Dih-Dih Huang, MD; and David Row, MD, FACS, FASCRS Dr. Zeitouni is with the Department of Dermatology at University of Arizona COM, Phoenix and Mohs and Reconstructive Surgery at Medical Dermatology Specialists, Phoenix, Arizona. Drs. Huang and Row are with the Department of Surgery at Creighton University School of […]

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The Michael Jackson and Winnie Harlow Effect: Impact on Vitiligo Awareness on the Internet

The Michael Jackson and Winnie Harlow Effect: Impact on Vitiligo Awareness on the Internet

| September 1, 2019

Dear Editor: Public awareness of diseases has been shown to increased when celebrities publicly disclose their own.1–3 Hugh Jackman’s public disclosure of his basal cell carcinoma diagnoses via social media is an example in dermatology.4 Here, we evaluated current trends on vitiligo, with emphasis on two celebrities with the condition: the late “King of Pop,” […]

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One-suture Eyelid Margin Repair: How Is It Done?

One-suture Eyelid Margin Repair: How Is It Done?

| September 1, 2019

Dear Editor: Eyelid margin defects are produced by injuries, burns, bites, scars, and benign and malignant lesions. In most cases, adjoining tissues are involved, which require flaps and/or tissue grafts carried out by a skilled surgeon (Figures 1 and 2). The eyelid comprises three layers: the anterior layer is composed of skin and the obicularis […]

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August 2019 Digital Edition

August 2019 Digital Edition

| August 1, 2019

Click the cover below to access the August 2019 digital edition of JCAD!

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Innumerable Squamous Cell Carcinomas in Vietnam War Veteran Exposed to Chemical Defoliants

Innumerable Squamous Cell Carcinomas in Vietnam War Veteran Exposed to Chemical Defoliants

| August 1, 2019

by Jennifer DeSimone, MD, and Meghan Beatson, BS Dr. DeSimone is with Inova Schar Cancer Institute in Fairfax, Virginia, and the Department of Dermatology at Virginia Commonwealth University School of Medicine in Richmond, Virginia. Ms. Beatson is with the George Washington University School of Medicine in Washington, DC; the Department of Dermatology at Alpert Medical […]

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