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The Journal of Clinical and Aesthetic Dermatology—Providing dermatologists with peer-reviewed, evidence-based information on the latest treatment options, new techniques, and practice management issues

Current Issue: May 2019

Selected Poster Abstracts from MauiDerm for Dermatologists 2019

Selected Poster Abstracts from MauiDerm for Dermatologists 2019

A message from the Guest Editor and MauiDerm Program Director, George Martin, MD Dear Colleagues: The 2019 edition of the MauiDerm for Dermatologists meeting had a variety of clinical and scientific data presented not only at the podium, but in its poster sessions as well. A wide range of clinically relevant material was presented in poster […]

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May 2019 Editorial Message

May 2019 Editorial Message

VOL. 12, NO. 5 • MAY 2019  Dear Colleagues:  Welcome to the May 2019 issue of The Journal of Clinical and Aesthetic Dermatology. We start this issue with a review article titled, “The Potential Uses of N-acetylcysteine (NAC) in Dermatology: A Review.” Here, Janeczek et al review clinical trials that assessed the efficacy of NAC […]

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The Potential Uses of N-acetylcysteine in Dermatology: A Review

The Potential Uses of N-acetylcysteine in Dermatology: A Review

J Clin Aesthet Dermatol. 2018;11(10):20–26 by Monica Janeczek, MD; Lauren Moy, MD; Alexandria Riopelle, BS; Olivia Vetter, BS; Jeave Reserva, MD; Rebecca Tung, MD; and James Swan, MD  Drs. Moy, Reserva, Tung, and Swan are with the Department of Dermatology at the Stritch School of Medicine at Loyola University Chicago in Maywood, Illinois. Mses. Janeczek, Riopelle, and […]

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Multiple Facial Lesions of Recalcitrant Pyoderma Gangrenosum Successfully Treated with Adalimumab

Multiple Facial Lesions of Recalcitrant Pyoderma Gangrenosum Successfully Treated with Adalimumab

 J Clin Aesthet Dermatol. 2019;12(5):28–32 by Raymond E. Kleinfelder, DO; Nady Hin, DO; Stefanie Cubelli, DO; Allan Snyder, PA-C; Francisco Kerdel, BSc, MBBS; and Brad Glick, DO, MPH Drs. Kleinfelder and Hin are with the Dermatology Residency Program at the LECOMT/Larkin Community Hospital, Palm Springs Campus, in Hialeah, Florida. Dr. Cubelli is with St. John’s Episcopal […]

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Efficacy of  Metformin  in the Treatment of Acne in Women with Polycystic Ovarian Syndrome:  A Newer Approach to Acne Therapy

Efficacy of Metformin in the Treatment of Acne in Women with Polycystic Ovarian Syndrome: A Newer Approach to Acne Therapy

J Clin Aesthet Dermatol. 2019;12(5):34–38 by SHILPI SHARMA, MD; DEEPAK K. MATHUR, MD; VIJAY PALIWAL, MD; and PUNEET BHARGAVA,MD All authors are with the Department of Dermatology, Venereology, and Leprology at SMS Medical College and Attached Hospitals in Jaipur, India. FUNDING: No funding was received for this study. DISCLOSURES: The authors have no conflicts of […]

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Evaluating the Efficacy, Safety, and Tolerability of the Combination of Tazarotene, Azelaic Acid, Tacrolimus, and Zinc Oxide for the Treatment of Melasma: A Pilot Study

Evaluating the Efficacy, Safety, and Tolerability of the Combination of Tazarotene, Azelaic Acid, Tacrolimus, and Zinc Oxide for the Treatment of Melasma: A Pilot Study

 J Clin Aesthet Dermatol. 2019;12(5)40–45 by Brandon Kirsch, MD; Paul M. Hoesly, MD; Anokhi Jambusaria, MD, MSCE; Michael G. Heckman, MS; Nancy N. Diehl, MS; and Jason C. Sluzevich, MD Drs. Kirsch (at the time of this study), Hoesly (at the time of this study), and Sluzevich are with the Department of Dermatology at the […]

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Past Articles

April 2019 Editorial Message

April 2019 Editorial Message

VOL. 12, NO. 3 • APRIL 2019 Dear Colleagues:  Welcome to the April 2019 issue of The Journal of Clinical and Aesthetic Dermatology. We start this issue with a review article by Martin, Young, and Aldredge titled, “Recommendations for Initiating Systemic Therapy in Patients with Psoriasis.” Here, the authors present a rationale for the utilization […]

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Recommendations for Initiating Systemic Therapy in Patients with Psoriasis

Recommendations for Initiating Systemic Therapy in Patients with Psoriasis

J Clin Aesthet Dermatol. 2019;12(4):13–26 by George Martin, MD; Melodie Young, MSN, ANP-C; and Lakshi Aldredge, MSN, ANP-BC Dr. Martin is with Dr. George Martin Dermatology Associates in Kihei, Hawaii. Ms. Young is with Modern Research Associates in Dallas, Texas. Ms. Aldredge is with the VA Portland Health Care System in Portland, Oregon. FUNDING: The authors […]

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Collision Tumor of Basal and Squamous Cell Carcinoma of the Palm

Collision Tumor of Basal and Squamous Cell Carcinoma of the Palm

 J Clin Aesthet Dermatol. 2019;12(4):28–30 by Charlene Lam, MD, MPH; Caitlyn Fuller, BA; Alexandra Flamm, MD; and Elizabeth M. Billingsley, MD All authors are with Penn State Hershey Medical Center in Hershey, Pennsylvania. FUNDING: No funding was received for this study. DISCLOSURES: The authors have no conflicts of interest relevant to the content of this article. […]

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Development of Periungual Pyogenic Granuloma with Associated Paronychia Following Isotretinoin Therapy: A Case Report and a Review of the Literature

Development of Periungual Pyogenic Granuloma with Associated Paronychia Following Isotretinoin Therapy: A Case Report and a Review of the Literature

 J Clin Aesthet Dermatol. 2019;12(4):32–36 by Conrad Benedetto, DO; Dave Crasto, MS; Leila Ettefagh, MD; Navid Nami, DO Drs. Benedetto, Ettefagh, and Nami are with the Western University of Health Sciences in Pomona, California; Mr. Crasto is with William Carey University College of Osteopathic Medicine in Hattiesburg, Mississippi. FUNDING: No funding was received for this […]

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Lithium-induced Linear Psoriasis: A Rare Presentation

Lithium-induced Linear Psoriasis: A Rare Presentation

J Clin Aesthet Dermatol. 2019;12(4):38–39 by Shimona Garg, MD; Anand Kumar, MD; Mala Bhalla, MD; Amrit Kaur, MD; and Raj Pal Singh Punia, MD Drs. Garg, Kumar, Bhalla and Kaur are with the Department of Dermatology, Venereology, and Leprosy and Dr. Punia is with the Department of Pathology—All from the Government Medical College and Hospital […]

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Randomized, Placebo-controlled Study of a Nutraceutical Based on Hyaluronic Acid, L-carnosine, and Methylsulfonylmethane in Facial Skin Aesthetics and Well-being

Randomized, Placebo-controlled Study of a Nutraceutical Based on Hyaluronic Acid, L-carnosine, and Methylsulfonylmethane in Facial Skin Aesthetics and Well-being

J Clin Aesthet Dermatol. 2019;12(4):40–45 by Ennio Guaitolini, MD; Attilio Cavezzi, MD; SteFania Cocchi, MD; Roberto Colucci, PhD; Simone Ugo Urso, MD; and Valentina Quinzi, MD Drs. Guaitolini, Cavezzi, Colucci, Urso, and Quinzi are with Eurocenter Venalinfa in San Benedetto del Tronto (AP), Italy. Drs. Guaitolini and Cocchi are with the Studio Medico Guaitolini-Cocchi in […]

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Online Exclusives

Fluorescent Light Energy: The Future for Treating Inflammatory Skin Conditions?

Fluorescent Light Energy: The Future for Treating Inflammatory Skin Conditions?

J Clin Aesthet Dermatol. 2019;12(5):E61–E68 by Deirdre Edge, PhD; Maiken Mellergaard, PhD; Carsten Dam-Hansen, PhD; Dennis Dan Corell, MSc; Joanna Jaworska, PhD; Giovanni Scapagnini, PhD; and Michael Canova Engelbrecht Nielsen, PhD Drs. Edge, Mellergaard, and Nielsen are with the Department of Research and Development at FB Dermatology, Ltd. in Ballerup, Denmark. Mellergaard is also with […]

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Retrospective Analysis of the Efficacy of 10,600nm Carbon Dioxide Laser Ablation for Small Congenital Melanocytic Nevi in Adults

Retrospective Analysis of the Efficacy of 10,600nm Carbon Dioxide Laser Ablation for Small Congenital Melanocytic Nevi in Adults

J Clin Aesthet Dermatol. 2019;12(4):E61–E63 by Jagdish Sakhiya, MD; Dhruv Sakhiya, MBBS; Ashish Dedakiya, MB, DDV; Rachiswayata Gupta, MD; Ravi Khambhati, MBBS, DVD; Pratik Sidhhpura, MD, VD; Feral Daruwala, M. Pharm; and Nimish Dudhatra, Msc Drs. J. Sakhiya, Dedakiya, Gupta, Khambhati, and Sidhhpura and Messrs. Daruwala, and Dudhatra are with Sakhiya Skin Clinic Pvt Ltd. in Surat, […]

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Vitamin C Prevents Ultraviolet-induced Pigmentation in Healthy Volunteers: Bayesian Meta-analysis Results from 31 Randomized Controlled versus Vehicle Clinical Studies

Vitamin C Prevents Ultraviolet-induced Pigmentation in Healthy Volunteers: Bayesian Meta-analysis Results from 31 Randomized Controlled versus Vehicle Clinical Studies

 J Clin Aesthet Dermatol. 2019;12(2):E53–E59 (epub only) by Romain de Dormael, PharmD;* Philippe Bastien, PhD;* Peggy Sextius, PhD; Audrey Gueniche, PharmD; Daniel Ye, PhD; Christian Tran, PharmD; Véronique Chevalier, MSc; Charles Gomes, PhD; Luc Souverain, MSc; and Caroline Tricaud, PhD Drs. de Dormael, Bastien, Sextius, Gueniche, Tran, Gomes, and Mr. Souverain are with L’Oréal Research […]

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In memory of  Vishwas (Vic) A. Narurkar, MD

In memory of Vishwas (Vic) A. Narurkar, MD

by W. Philip Werschler, MD, FAAD, FAACS Dr. Werschler is Aesthetic Dermatology Editor-In-Chief of the Journal of Clinical and Aesthetic Dermatology and is Assistant Clinical Professor of Medicine/Dermatology University of Washington School of Medicine in Seattle, Washington. J Clin Aesthet Dermatol. 2019;12(2):E60–62 epub only I first met Vic Narurkar when we were both young and […]

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Management of Necrosis

Management of Necrosis

Management of Necrosis by Martyn King, MD

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Visual Loss Secondary to Cosmetic Filler Injection

Visual Loss Secondary to Cosmetic Filler Injection

Visual Loss Secondary to Cosmetic Filler Injection Lee Walker, MD and Martyn King, MD  

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In Focus

Topical Ivermectin: Data Supporting Dual Modes of Action in Rosacea

Topical Ivermectin: Data Supporting Dual Modes of Action in Rosacea

by James Q. Del Rosso, DO, FAOCD, FAAD Dr. Del Rosso is Research Director at JDR Dermatology Research in Las Vegas, Nevada; Adjunct Clinical Professor of Dermatology at Touro University Nevada, Las Vegas; and with Dermatology and Cutaneous Surgery at Thomas Dermatology in Las Vegas, Nevada. Funding: The author did not receive any form of […]

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Topical Alpha-Agonist Therapy for Persistent Facial Erythema of Rosacea and the Addition of Oxmetazoline to the Treatment Armamentarium: Where Are We Now?

Topical Alpha-Agonist Therapy for Persistent Facial Erythema of Rosacea and the Addition of Oxmetazoline to the Treatment Armamentarium: Where Are We Now?

by James Q. Del Rosso, DO, FAOCD, FAAD Dr. Del Rosso is Research Director at JDR Dermatology Research, Las Vegas, Nevada and at Henderson Dermatology Research in Henderson, Nevada; is Adjunct Clinical Professor (Dermatology) at ableouro University Nevada, Las Vegas, Nevada; and practices Dermatology and Cutaneous Surgery at Thomas Dermatology in Las Vegas, Nevada. J […]

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A Closer Look at Seborrheic Keratoses: Patient Perspectives, Clinical Relevance, Medical Necessity, and Implications for Management

A Closer Look at Seborrheic Keratoses: Patient Perspectives, Clinical Relevance, Medical Necessity, and Implications for Management

James Q. Del Rosso, DO, FAOCD, FAAD Research Director, JDR Dermatology Research and Private Dermatology Practice, Thomas Dermatology, Las Vegas, Nevada Disclosure: Dr. Del Rosso serves as a consultant to Aclaris Therapeutics, Inc. (Malvern, Pennsylvania) that  has a topical therapy for seborrheic keratosis under development. He also served as a consultant for and as the […]

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Emerging Issues in Adult Female Acne

Emerging Issues in Adult Female Acne

aJoshua A. Zeichner, MD; bHillary E. Baldwin, MD; cFran E. Cook-Bolden, MD; dLawrence F. Eichenfield, MD; dSheila Fallon-Friedlander, MD; eDavid A. Rodriguez, MD aMount Sinai Hospital, New York, New York bMorristown, New Jersey cSkin Specialty Dermatology, New York, New York dUniversity of California, Rady Children’s Hospital, San Diego, California eDermatology Associates/Research, Coral Gables, Florida; cRedwood […]

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Oral Apremilast for the Treatment  of Plaque Psoriasis

Oral Apremilast for the Treatment of Plaque Psoriasis

James Q. Del Rosso, DO; Leon Kircik, MD Disclosures (related to this manuscript): Dr. Del Rosso is a speaker, consultant, and/or researcher for Anacor, Aqua, Allergan, Bayer, Celgene, Galderma, LeoPharma, Novartis, Pharmaderm, Promius, SunPharma, and Valeant. Dr. Kircik is either a speaker, consultant, or investigator for Amgen, Anacor, Aqua, Allergan, Bayer, Celgene, Coherus, Eli Lilly, […]

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Application of Nail Polish During Topical Management of Onychomycosis Are Data Available to Guide the Clinician  About What to Tell Their Patients?

Application of Nail Polish During Topical Management of Onychomycosis Are Data Available to Guide the Clinician About What to Tell Their Patients?

James Q. Del Rosso, DO, FAOCD, FAAD Adjunct Clinical Professor (Dermatology), Touro University Nevada, Henderson, Nevada; Research Director, Del Rosso Dermatology Research, Las Vegas, Nevada; Private Practice, Lakes Dermatology, Las Vegas, Nevada Disclosure: Dr. Del Rosso served as the sole author of this manuscript. No individual or group from any company or agency participated in […]

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Recent Posts

May 2019 Digital Edition

May 2019 Digital Edition

| May 1, 2019

Click the cover below to access the May 2019 digital edition of JCAD!

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Willingness-to-pay and Time Trade-off: The Burden of Disease in Patients with Benign Hyperpigmentation

Willingness-to-pay and Time Trade-off: The Burden of Disease in Patients with Benign Hyperpigmentation

| May 1, 2019

 J Clin Aesthet Dermatol. 2019;12(5):46–48 by Mayra B. C. Maymone, MD, DSc; Susruthi Rajanala, BA; Rafael Widjajahakim, MS; Eric Secemsky, MD, MSc; Dana Saade, MD; and Neelam A. Vashi, MD Drs. Maymone, Saade, and Vashi, Ms. Rajanala, and Mr. Widjajahakim are with the Department of Dermatology at the Boston University School of Medicine in Boston, Massachusetts. […]

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What’s new in the medicine chest? More from the Pipeline of Clinical Research on Selected Systemic Therapies for Atopic Dermatitis

What’s new in the medicine chest? More from the Pipeline of Clinical Research on Selected Systemic Therapies for Atopic Dermatitis

| May 1, 2019

 J Clin Aesthet Dermatol. 2019;12(5):49–53 This ongoing column explores emerging treatment options, drug development trends, and pathophysiologic concepts in the field of dermatology. by James Q. Del Rosso, DO Dr. Del Rosso is Research Director of JDR Dermatology Research in Las Vegas, Nevada; is with Thomas Dermatology in Las Vegas, Nevada; and is Adjunct Clinical […]

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Geographic Tongue Induced by Venetoclax in a Patient with Chronic Lymphocytic Leukemia

Geographic Tongue Induced by Venetoclax in a Patient with Chronic Lymphocytic Leukemia

| May 1, 2019

by Andrew J. Krispinsky, MD; Polina V. Rzepka, MD; Farrukh Awan, MD; and Benjamin H. Kaffenberger, MD Drs. Krispinsky, Rzepka, and Kaffenberger are with the Division of Dermatology and Dr. Awan is with the Division of Hematology­— all from the Department of Internal Medicine at The Ohio State University Comprehensive Cancer Center in Columbus, Ohio. Funding/disclosures. Dr. Awan […]

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Recurrence of Localized Pemphigus Foliaceus Induced by Knee Replacement

Recurrence of Localized Pemphigus Foliaceus Induced by Knee Replacement

| May 1, 2019

J Clin Aesthet Dermatol. 2019;12(5):11–18 by Nima Milani-Nejad MD, PhD; Catherine Chung, MD; and Jessica Kaffenberger, MD All authors are with the Division of Dermatology in the Department of Internal Medicine at The Ohio State University Wexner Medical Center in Columbus, Ohio.  Funding/disclosures. Dr. Kaffenberger is a principal investigator for AbbVie, AnaptysBio, Bristol-Myers, Cara Therapeutics, Celgene, Corrona, Eli […]

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