Welcome to the November 2017 issue of the Journal of Clinical and Aesthetic Dermatology (JCAD). We start this issue with a study by Sidgiddi et al titled “Treatment Satisfaction, Product Perception, and Quality of Life in Plaque Psoriasis Patients Using Betamethasone Dipropionate Spray 0.05%.” Here, the authors assess the patient-reported satisfaction, efficacy, and tolerability associated with the use of betamethasone dipropionate spray 0.05% when applied twice daily in subjects with moderate plaque psoriasis. The authors found that betamethasone dipropionate spray 0.05% demonstrated good levels of patient satisfaction and quality of life measures, in combination with improvements in the global assessment of disease and the level of itching experienced by subjects.
Following this, Kollipara et al investigates differences in lip measurements and preferences of Asians and Hispanics compared with those of Caucasians in their article titled “Lip Measurements and Preferences in Asians and Hispanics: A Brief Review.” The authors discuss the disadvantages of using Caucasian measurements and generalizations in lip preferences when determining treatment goals for the aesthetic augmentation of lips among Asians and Hispanics, as preferences and measurements can vary greatly between ethnicities.
Next, Ditre et al address the clinical effectiveness of OxyGeneo™, a noninvasive skin oxygenation treatment, on skin texture, fine lines, and skin pigmentation over an eight-week period. All patients included in their study, titled “OxyGeneo®—A Unique Three-in-one Treatment of Exfoliation, Infusion, and Oxygenation via the Bohr Effect and TriPollar™ Radiofrequency for Skin Rejuvenation,” saw an improvement in overall skin appearance, skin texture, brightness, and shininess after the eight-week period. The majority of all patients reported an increased softness in their skin, along with a more youthful appearance, minor improvement in appearance of fine lines and wrinkles, and improvement in skin pigmentation.
Following this, in their study titled “Three-day Field Treatment with Ingenol Disoxate (LEO 43204) for Actinic Keratosis: Cosmetic Outcomes and Patient Satisfaction from a Phase II Trial,” Berman et al report cosmetic outcomes on the face and chest, scalp, or trunk and extremities, with ingenol disoxate used in a once-daily, three-day field treatment regimen in patients with actinic keratosis. Improved overall appearance of the treatment area was reported by 95, 97, and 80 percent of patients in the face/chest, scalp, and trunk/extremities groups, respectively. The authors also report high treatment adherence and high treatment satisfaction among patients.
Next, Amer et al share results from their study, “Doppler versus Histopathology in the Assessment of Egyptian Patients with Psoriasis Treated with Acitretin.” Here, the investigators evaluated the effect of Doppler sonography in the assessment of psoriasis in comparison with histopathology while treating 30 patients with chronic plaque psoriasis with acitretin for a 12-week period. The authors reported a notable decrease in psoriatic plaques in all patients treated with acitretin and concluded that there were significant correlations between sonography and histopathology in the diagnosis and evaluation of a psoriatic skin treatment regimen.
Following this, in a study by Del Campo et al titled “Effect of Miracle Fruit (Synsepalum dulcificum) Seed Oil (MFSO®) on the Measurable Improvement of Hair Breakage in Women with Damaged Hair: A Randomized, Double-blind, Placebo-controlled, Eight-month Trial,” the authors assess the safety and efficacy of a hair oil containing MFSO and its effects on hair breakage rates for eight months, with the primary efficacy endpoints being the percent change in Healthy Hair Index 75 and Healthy Hair Index 50 measurements from baseline to the eighth month. The authors report significant improvements in hair breakage reduction, concluding that MFSO hair oil product is a safe and effective option for the treatment of women suffering from hair breakage and damaged hair.
And finally, Elstrom et al describe the case of a 56-year-old male patient with a recalcitrant recurrent distal leg ulcer, treated initially with debridement and compression therapy, and then subsequently with hyaluronic acid sodium salt 0.2% gel, which prompted complete wound closure. The authors hope that this study encourages more research into hyaluronic acid as a safe, efficacious, expeditious, and cost-effective option for the management of recalcitrant chronic ulcers.
We hope you enjoy this issue of JCAD. As always, we welcome your feedback and submissions.
James Q. Del Rosso, DO, FAOCD
Editor-in-Chief, Clinical Dermatology
Wm. Philip Werschler, MD, FAAD, FAACS
Editor-in-Chief, Aesthetic Dermatology
Seemal R. Desai, MD, FAAD