Expert insights on dietary supplementation with rosemary extract and the impact on skin quality from the inside out.

Episode 5—Giuseppe Valacchi, PhD: BioRewind Skin Health Dietary Supplement—Reversal of Glycation in the Skin—Histological Evidence

Dr. Valacchi reviews histological findings from a study published in the March 2025 issue of Journal of Clinical and Aesthetic Dermatology that investigated the effects of a dietary supplement containing rosemary extract on biomarkers associated with skin glycation and oxinflammation.

Using skin biopsies and tape-strip analysis, the study evaluated whether targeted nutritional intervention could help reverse processes linked to the formation of advanced glycation end products (AGEs) and inflammation-related skin aging.

Topics Covered

  • Histological evidence related to skin glycation reversal
  • The role of oxinflammation and AGEs in visible skin aging
  • Biomarker analysis using skin biopsies and tape-strip techniques
  • Potential effects of rosemary extract on skin health and inflammation pathways

Reference
Guiotto A, et al. Reversing Oxinflammation Associated with Glycative Stress and Formation of Advanced Glycation End Products with a Dietary Supplement Containing Rosemary Extract. Journal of Clinical and Aesthetic Dermatology. 2025;18(3):34–38.

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