J Clin Aesthet Dermatol. 2023;16(1):14-17. by Karen Konkel, MD; Melissa Reyes, MD,
Background. Dr. Frederic Mohs believed that surgery can spread a melanoma; to prevent this, he applied an inactive black paste vehicle containing the active ingredient 50% zinc chloride solution to melanomas to kill and fix (i.e., preserve) tissue; this is termed fixed-tissue surgery.
J Clin Aesthet Dermatol. 2019;12(1):28–31 by Andrew Duncanson, DO; Michael Kopstein, DO;