J Clin Aesthet Dermatol. 2021;14(2):12–13. Dear Editor: In their recent article, Lowery et al1 argue that iPLEDGE should remove abstinence as a contraceptive method, requiring individuals with reproductive potential to instead use medical contraception, regardless of sexual activity. We feel this change would be unlikely to significantly reduce fetal isotretinoin exposure, raises unacceptable ethical concerns, […]

J Clin Aesthet Dermatol. 2021;14(2):12–13. Dear Editor: iPLEDGE, the risk evaluation and mitigation strategy program for isotretinoin, has been criticized for being unnecessarily complex, antiquated, and ineffective. It mandates that those with ovaries and a uterus who are premenopausal either take two forms of contraception or sign an abstinence pledge when starting isotretinoin. In a […]

Dear Editor: There is no doubt now that the use of botulinum toxin (BoNT) in aesthetics has been a revolution for the noninvasive treatment of patients. In the last several decades, the use of BoNT has changed from fixed doses delivered at fixed time intervals into fixed anatomical sites, all of which were required for […]

Dear Editor: We are writing to highlight the interesting but little explored interaction between sleep and melasma, a common dermatological disease that causes a major impact on several areas of the lives of individuals with the condition. Melasma causes skin hyperpigmentation and is characterized by symmetric hypermelanosis of sun-exposed skin represented by brown macules and […]

Dear Editor: We read the recent article, “Recurrence of Localized Pemphigus Foliaceus Induced by Knee Replacement,” with great interest.1 The authors attribute the presentation of unilateral pemphigus foliaceus (PF) in a previously uninvolved site to an immunocompromised district (ICD), where edema and nerve injury paved the way for a buildup of immunoglobulins and immune cells. […]

Dear Editor: Onychocryptosis, or ingrown nail (IN) is a common problem in dermatology clinical practice. Its prevalence is estimated to be from 2.5 to 5 percent, with a predominance in males.1 The incidence has a bimodal age-related peak: it appears to be higher among teenagers and young adults, but also shows a strong predominance in […]

Dear Editor: No other single medical product has revolutionized and quite literally defined the aesthetic medicine field like botulinum toxin injections.1–5 Every year, a growing number of patients experience the cosmetic benefits of neurotoxin products as indications for use expand and new formulations are introduced into the marketplace.6 The vast clinical experience gained over the […]