Amy McMichael, MD: Use of Deuruxolitinib for Hair Regrowth in Patients With Alopecia Areata

Amy McMichael, MD, a clinical professor and chair of the Department of Dermatology at Wake Forest School of Medicine, discusses the trials for deuruxolitinib, an FDA-approved treatment for alopecia areata. Deuruxolitinib has shown significant improvement in clinical trials compared to placebo, with a twice-daily dose of 8 mg. The trials, which included adults of various ethnicities, showed no serious adverse events, though herpes zoster and upper respiratory infections were noted. Deuruxolitinib is 1 of 3 other Janus kinase inhibitors for severe alopecia areata, offering a safer alternative to long-term corticosteroids and improving patients’ quality of life by regrowing hair and enhancing overall well-being.

MORE EXPERT PERSPECTIVES IN ALOPECIA AREATA:

Ted Lain, MD, MBA: Reviewing Results of the THRIVE-AA1 Trial in Severe Alopecia Areata

Ted Lain, MD, MBA, a board-certified dermatologist at Sanova Dermatology in Austin, Texas, discusses the randomized phase 3 THRIVE-AA1 trial (NCT04518995), which assessed the safety

Aaron Farberg, MD: Use of JAK Inhibitors for Alopecia Areata Treatment

Dr. Farberg explores the evolving treatment landscape for alopecia areata, with a focus on JAK inhibitors and their role in selectively targeting immune pathways involved

Paradi Mirmirani, MD: Addressing Treatment Gaps for Patients with Alopecia Areata

Dr. Mirmirani examines the current treatment landscape for extensive and severe alopecia areata, focusing on longstanding unmet needs and how recent FDA-approved therapies are beginning

Arash Mostaghimi, MD, MPH, FAAD: Assessing the Safety and Efficacy of Deuruxolitinib in Patients with Alopecia Areata

Dr. Mostaghimi reviews pivotal data from the Phase 3 THRIVE-AA1 and THRIVE-AA2 clinical trials, which evaluated the safety and efficacy of deuruxolitinib in patients with