Dr. Bhutani reviews the underlying disease mechanisms of Generalized Pustular Psoriasis (GPP), focusing on the role of inflammatory signaling pathways that drive the condition. Her discussion highlights how elevated levels of Interleukin-36 cytokines contribute to the pathogenesis of GPP by triggering excessive inflammation within affected skin lesions.
Topics Covered
- The immunologic drivers behind generalized pustular psoriasis
- The role of IL-36 cytokines in promoting inflammatory responses
- How dysregulated immune signaling contributes to pustule formation
- Why understanding disease mechanisms helps guide targeted therapies
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