James Del Rosso, DO, and Christopher Bunick, MD: Tralokinumab as a Therapeutic Alternative for Dupilumab-associated Arthralgia in Atopic Dermatitis—A Multi-center Case Series

Drs. Bunick and Del Rosso discuss a case series published in the May 2025 issue of The Journal of Clinical and Aesthetic Dermatology that describes arthralgia in 15 patients with atopic dermatitis who were treated with dupilumab, who subsequently saw resolution in symptoms after switching to tralokinumab. 

Time Stamps:
[0:00] Introduction
[2:09] Chapter 1: Acknowledging the diversity of drugs within a dermatologic drug class
[4:54] Chapter 2: An overview and notable aspects of this JCAD case series
[7:45] Chapter 3: Clinical tips for identifying and navigating treatment-related adverse events in patients with atopic dermatitis
[14:05] Chapter 4: Atopic dermatitis symptom improvement in case series patients switching from dupilumab to tralokinumab

Reference:

1. Greenberg ABW, Shahriari M, Cameron, et al. Tralokinumab as a Therapeutic Alternative for Dupilumab-associated Arthralgia in Atopic Dermatitis: A Multi-center Case Series. J Clin Aesthet Dermatol. 2025;18(5):16–19.