George Han, MD, PhD, and Zoe Diana Draelos, MD: Protecting the Skin Barrier with Moisturization in Patients with Sensitive Skin

Drs. Han and Draelos evaluate pre-clinical and clinical studies that demonstrate the effectiveness of moisturizers in improving the skin barrier in patients with sensitive skin.

References:

1. Bernhardt et al. Novel Natural Moisturizing Factor and Lipid-Containing Face Cream Induces Aquaporin-3 and Filaggrin Expression Associated With Barrier Improvements and Sustained Clinical Hydration in Extra- Dry Skin. Presented at: 2024 American Academy of Dermatology Annual Meeting; March 8-12, 2024; San Diego, California.
2. Zaleski et al. Barrier-Supporting NMF-Containing Face Gel and NMF + Lipid-Containing Face Cream Improve Disease and Medication-Induced Irritation in Sensitive Skin Patients. Presented at: 2024 Society for Investigative Dermatology Annual Meeting; May 15-18, 2024; Dallas, Texas.
3. Parsa et al. Tretinoin and retinol bioactivity are retained when layered with adjunctive water gel moisturizer or a water cream moisturizer in an “open sandwich” regimen. Presented at: American Academy of Dermatology Annual Meeting; March 7-11, 2025; Orlando, Florida.