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Background. Dr. Frederic Mohs believed that surgery can spread a melanoma; to prevent this, he applied an inactive black paste vehicle containing the active ingredient 50% zinc chloride solution to melanomas to kill and fix (i.e., preserve) tissue; this is termed fixed-tissue surgery.
J Clin Aesthet Dermatol. 2020;13(2):53–57 by Polytimi Sidiropoulou, MD; Stamatis Gregoriou, MD, PhD; Dimitris Rigopoulos, MD, PhD; and Georgios Kontochristopoulos, MD, PhD Drs. Sidiropoulou, Gregoriou and Rigopoulos are with the 1st Department of Dermatology-Venereology of the National and Kapodistrian University of Athens at Andreas Syggros Hospital for Cutaneous & Venereal Diseases in Athens, Greece. Dr.
J Clin Aesthet Dermatol. 2020;13(1):41–43 by Dante Garcia, MD; Itisha S. Jefferson, BS; Pablo Ramirez, BS; Angelina Palomino, BS; William Adams, PhD; Jessica Vera, BSN; Ruby De La Torre, APN; Kristin Lee, MD; Ashley Elsensohn, MD, MPH; Hana Kazbour, MD; and Rebecca Tung, MD Dr. Garcia is with the Department of Internal Medicine at Loma