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Eliminating Abstinence in iPLEDGE: A Dereliction of Medical Ethics?

J Clin Aesthet Dermatol. 2021;14(2):12–13. Dear Editor: In their recent article, Lowery et al1 argue that iPLEDGE should remove abstinence as a contraceptive method, requiring individuals with reproductive potential to instead use medical contraception, regardless of sexual activity. We feel this change would be unlikely to significantly reduce fetal isotretinoin exposure, raises unacceptable ethical concerns,

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Letter to the Editor: Amending iPLEDGE: Why “Abstaining from Abstinence” May Harm LGBTQ+ Patients

J Clin Aesthet Dermatol. 2021;14(2):12–13. Dear Editor: iPLEDGE, the risk evaluation and mitigation strategy program for isotretinoin, has been criticized for being unnecessarily complex, antiquated, and ineffective. It mandates that those with ovaries and a uterus who are premenopausal either take two forms of contraception or sign an abstinence pledge when starting isotretinoin. In a

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